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		<h1 class="catchCopy">リウマチ・膠原病疾患の臨床写真等を網羅したアトラス！</h1>
		

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					著：廣畑俊成（信原病院副院長，北里大学客員教授，帝京大学客員教授）
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				<ul class="property"><li class="disc">B5判・200頁・4色刷</li><li class="disc">ISBN&nbsp;978-4-8306-2045-4</li><li class="disc">2018年4月6日発行</li></ul>

				
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		<div class="headers"><h3 class="current content">内容</h3><h3 class="preface">序文</h3><h3 class="indexes">主要目次</h3></div><section class="current content">リウマチ・膠原病診療の第一線を走り続ける著者が，その長年の診療経験をまとめたアトラス．リウマチ・膠原病領域の24疾患と，関連する変形性膝関節症，リウマチ熱などを「その他」としてまとめ，それぞれの臨床写真・画像検査写真・病理写真を網羅している．リウマチ・膠原病医だけなく，その専門医を目指す読者も必携の１冊．</section><section class="preface">はじめに<br><br>　膠原病は全身のあらゆる臓器を侵す疾患である．そのためその診断にあたっては，漏れのない病歴の聴取に加えて，注意深い全身の診察が必要である．また，膠原病の診療にあたっては，その病態や病理をよく理解することが役に立つことは疑いのないことである．そのためには，X線，超音波，CT，MRIなどの検査の評価に加えて，種々の臓器の病理組織所見を知っておくことは極めて重要である．<br>　この30年の間には，他の分野と同様に膠原病領域の臨床も大きな進歩を遂げた．それに伴い知っておくべき臨床症候，検査所見，病理所見も大幅に増加している．さらに，免疫学の進歩に伴い，膠原病・膠原病類縁疾患のそれぞれの病態生理についても理解が深まっている．また，免疫抑制療法やステロイド治療の副作用として色々な問題が派生しており，それに対しても臨床医は適切な対応を迫られている．このような膨大な知識を習得するためには日常の臨床経験だけではなかなか困難な場合が多い．それは膠原病の中には有病率の低い希少疾患もかなり含まれているからである．<br>　2年前，膠原病の基礎知識をなるべく時間をかけずに習得することの助けになるように，「リウマチ・膠原病診療ガイド」を出版させていただいた．今回は，そのコンセプトを受け継ぎつつ，できるだけ多くの臨床症候，画像検査所見，病理組織所見の実際を読者の皆様に見ていただけるように，アトラスとして出版させていただくことになった．本書に収載されている写真はすべて，小生が卒業以来種々の施設で経験させていただいたものばかりである．こうした自分自身の経験が，膠原病診療を志す医師・看護師・薬剤師・その他のパラメディカルスタッフの方々にとって，少しでもお役にたてばこれ以上の喜びはない．<br>　最後に本書の執筆の機会を与えて頂いた文光堂の浅井麻紀社長・小柳　健氏をはじめとする関係者の方々，およびこれまで共に診療に携ってきた東京大学，帝京大学，北里大学の諸先生に深謝したい．また，病理標本の所見について色々とご指導下さった東北大学名誉教授，故・京極方久先生に深謝するとともに，心からご冥福をお祈りしたい．<br><br>平成30年3月<br>廣畑俊成</section><section class="indexes">はじめに<br>1　関節リウマチ<br>　滑膜の増殖<br>　滑膜の病理組織像<br>　手の臨床所見<br>　肘関節の臨床所見<br>　皮下結節と手の伸筋腱断裂<br>　膝関節の臨床所見<br>　足の変形<br>　環軸椎亜脱臼<br>　合併症<br>　RAと特発性器質化肺炎（COP）<br>　メトトレキサート（MTX）肺炎<br>　ニューモシスチス肺炎（PCP）<br>　TNF阻害薬による滑膜の変化<br>　RAと変形性関節症（OA）の鑑別<br>　RAとOAの滑膜の病理組織像の比較<br>2　悪性関節リウマチ<br>　末梢神経障害<br>　皮下結節<br>　皮下出血と爪周囲出血・上強膜炎<br>　皮膚潰瘍・心筋梗塞<br>　心膜炎・胸膜炎<br>　間質性肺炎<br>3　全身性エリテマトーデス<br>　蝶形紅斑と円板状紅斑<br>　種々の紅斑<br>　皮疹の組織像<br>　口腔内潰瘍と関節炎<br>　手の変形<br>　心膜炎と胸膜炎<br>　肺胞出血<br>　腎障害<br>　ループス腹膜炎<br>　眼底の血管炎と大腿骨頭壊死<br>4　ループス腎炎<br>　ループス腎炎の組織型<br>　肺胞出血とループス腎炎<br>5　中枢神経ループス<br>　Acute confusional state（急性錯乱状態）<br>　Demyelinating syndrome（脱髄病変）<br>　Myelitis（脊髄炎）<br>　脳幹と大脳の血管炎<br>　Autonomic disorder（自律神経障害）<br>　PRES（可逆性白質脳症）とRCVS（可逆性脳血管攣縮症候群）<br>6　抗リン脂質抗体症候群<br>　出血性脳梗塞<br>　脳梗塞と末梢神経障害<br>7　全身性硬化症（強皮症）<br>　特徴的な臨床症状<br>　病理組織像<br>　レイノー現象と限局型SSc<br>　指の血行障害による変化<br>　指の種々の変化<br>　消化管の運動異常<br>　腸管囊気腫症<br>　間質性肺炎<br>　心不全とGAVE<br>　心膜炎と肺高血圧<br>　SSc腎クリーゼ<br>　SScの鑑別疾患<br>8　多発筋炎・皮膚筋炎<br>　筋肉の画像と病理<br>　ヘリオトロープ疹とゴットロン徴候<br>　ゴットロン徴候<br>　非定型的な皮疹<br>　爪周囲紅斑<br>　mechanic's hand<br>　間質性肺炎（びまん性肺胞障害）<br>　びまん性肺胞障害と縦隔気腫<br>9　混合性結合組織病<br>　手指の症状<br>　肺高血圧症<br>10　シェーグレン症候群<br>　唾液腺の病変<br>　唾液腺シンチグラフィーと蛍光色素試験<br>11　IgG4関連疾患<br>　涙腺・顎下腺の病変<br>　種々の臓器病変<br>　病理組織像<br>　キャッスルマンリンパ腫<br>12　ベーチェット病<br>　再発性口腔内アフタ性潰瘍<br>　外陰部潰瘍<br>　皮膚症状と針反応<br>　眼病変<br>　関節炎<br>　血管病変<br>　肺動脈瘤破裂の剖検所見<br>　腸管病変<br>　急性型神経ベーチェット病<br>　慢性進行型神経ベーチェット病の画像所見<br>　慢性進行型神経ベーチェット病の病理組織像<br>13　血清反応陰性脊椎関節症<br>　仙腸関節炎<br>　乾癬性関節炎<br>　掌蹠膿疱症<br>14　結晶性関節炎<br>　痛風・偽痛風の病因と病理<br>　偽痛風<br>　痛風<br>　痛風結節<br>15　再発性多発軟骨炎<br>　臨床症状<br>　気道の狭窄<br>　検査所見・病理組織像<br>16　成人スティル病<br>　リウマトイド疹（サーモンピンク疹）<br>　心肺合併症<br>　その他の症状<br>　成人スティル病に酷似した病像を呈した<br>　悪性リンパ腫<br>17　リウマチ性多発筋痛症・RS3PE症候群<br>　PMR<br>　RS3PE症候群<br>18　側頭動脈炎<br>　浅側頭動脈の異常<br>　病理組織像<br>19　高安動脈炎<br>　大動脈の分枝の狭窄<br>　肺動脈病変<br>　病理組織像<br>20　古典的結節性多発動脈炎<br>　皮下結節と精巣上体炎<br>　皮膚・筋肉の病理組織像<br>　腹部の血管炎<br>　四肢にみられた動脈瘤と破裂<br>　腸管病変と神経病変<br>　皮膚型の古典的PN<br>21　顕微鏡的多発血管炎<br>　皮膚症状<br>　肺胞出血<br>　半月体形成性糸球体腎炎<br>　中枢神経病変<br>22　多発血管炎性肉芽腫症<br>　頭頸部の肉芽腫<br>　肺の肉芽腫<br>　腎病変・肥厚性硬膜炎<br>　中枢神経病変<br>23　好酸球性多発血管炎性肉芽腫症<br>　末梢神経障害<br>　皮膚病変<br>24　IgA血管炎<br>　四肢の紫斑<br>　紫斑・合併症<br>25　その他<br>　リウマチ熱<br>　帯状疱疹・ニューモシスチス肺炎（PCP）<br>　非定型肺炎<br>　粟粒結核<br>　骨粗鬆症<br>　メトトレキサート（MTX）誘発悪性リンパ腫<br>索　引</section></article>
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