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		<span class="magazineCopy">病理と臨床&nbsp;&nbsp;2022年臨時増刊号（40巻）</span>
		
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			<div class="headers"><h3 class="current indexes">主要目次</h3></div><section class="current indexes">第1部　がんの分子病理学（序論）<br>　A．がんの分子生物学<br>　　1　ゲノムの構成<br>　　2　遺伝子バリアントの表記方法<br>　　3　がん遺伝子とがん抑制遺伝子<br>　　4　エピジェネティクス（1）メチル化異常<br>　　5　エピジェネティクス（2）ヒストン修飾の異常<br>　　6　エピジェネティクス（3）RNAによる制御<br>　　7　遺伝子異常と多段階発がん<br>　B．解析法<br>　　1　FISH・ISH<br>　　2　分子病理学的検索のための核酸抽出<br>　　3　PCR法<br>　　4　ヒトゲノム研究におけるマイクロアレイ解析（CGH・SNP・メチル化など）<br>　　5　次世代シークエンシング（1）次世代シークエンシングの原理<br>　　6　次世代シークエンシング（2）がんゲノム医療における変異解析<br>　　7　次世代シークエンシング（3）RNAシークエンシング解析<br>　　8　次世代シークエンシング（4）リキッドバイオプシー<br><br>第2部　腫瘍発生にかかわる分子機構<br>　　1　WNTシグナル経路<br>　　2　MAPK経路<br>　　3　PI3K/AKT/mTOR経路<br>　　4　TGF-β経路<br>　　5　細胞周期とチェックポイント制御因子<br>　　6　DNA修復機構<br><br>第3部　がんの分子病理学（各論）<br>　A．家族性腫瘍<br>　　1　Lynch症候群<br>　　2　遺伝性びまん性胃がん<br>　　3　遺伝性乳癌卵巣癌症候群<br>　　4　Li-Fraumeni症候群<br>　　5　家族性大腸腺腫症<br>　　6　多発性内分泌腫瘍症<br>　B．臓器がん<br>　　1　脳腫瘍<br>　　2　頭頸部がん・口腔がん<br>　　3　唾液腺腫瘍<br>　　4　甲状腺がん<br>　　5　食道がん<br>　　6　胃がん<br>　　7　大腸がん<br>　　8　GIST<br>　　9　肝細胞がん<br>　　10　胆道がん<br>　　11　膵がん<br>　　12　肺がん<br>　　13　乳がん<br>　　14　腎がん<br>　　15　尿路がん<br>　　16　前立腺がん<br>　　17　子宮体がん<br>　　18　子宮頸がん<br>　　19　卵巣がん<br>　　20　骨軟部腫瘍<br>　　21　皮膚腫瘍・悪性黒色腫<br>　　22　悪性中皮腫<br>　　23　白血病<br>　　24　リンパ腫<br><br>第4部　遺伝子パネル検査<br>　　1　がんゲノム医療の制度<br>　　2　がんゲノム医療（1）OncoGuideTM NCCオンコパネルシステムの特徴<br>　　3　がんゲノム医療（2）FoundationOne® CDxがんゲノムプロファイルの特徴<br>　　4　がんゲノム医療（3）血中循環腫瘍DNA（ctDNA）を用いたがん遺伝子パネル検査の特徴<br>　　5　小児・AYAがん遺伝子パネル検査の展望<br>　　6　造血器遺伝子パネル検査の展望<br>　　7　遺伝性腫瘍に対する多遺伝子パネル検査<br><br>終わりに―がんの遺伝子診断の未来―<br><br>索引</section></article>
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